Following the lives of people weighing over 600 pounds as they embark on an incredible weight-loss journey to try and turn their lives around forever.
Krystal began overeating to shield herself with a protective layer after years of abuse. Once a means of protection, her eating habits might now kill her.
Isaac helped raise his siblings after his mother suffered a stroke. While learning to cook for his family, he picked up life-changing eating habits.
A lifetime of abuse has left Michael anxious to leave the house. With Dr. Now's assistance, he dramatically alters his lifestyle to try and save his life.
Shannon is 700-lbs and bedridden and without Dr. Now's help, her life is at risk. But, when the global pandemic strikes, Shannon's weight-loss journey is paused.
Irene had to move back in with her son because her weight made it unbearable to live on her own. Dr. Now is unable to get through to her.
Tammy's two daughter have put their lives on hold to care for their mother. Can Dr. Now help Tammy confront her grief and overcome her eating disorder?
Chrystal is unable to shower without assistance from her teenage daughter. Can Dr. Now help her confront childhood trauma and turn her around her life?
Ryan has lost his job and spends most of his time on a large recliner. He is determined not to suffer the same fate as his father, who died weighing...
Paul weighs in at 700-lbs and his girlfriend struggles with how his weight limits their life together. He worries the relationship won't survive his time in Houston.
Despite being so big from overeating that she can barely leave the house, Lacey has found love with Ricky. But his interfering sister is complicating things.
Mike gained over 700lbs after his football dreams were dashed by multiple concussions. Now he must find a new purpose in life to avoid succumbing to pain and regret.